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À propos de : Regioselective Synthesis of Polysubstituted Pyrazoles andIsoxazoles        

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  • Regioselective Synthesis of Polysubstituted Pyrazoles andIsoxazoles
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  • A regioselective synthesis has been developed for the preparation of unsymmetrical 1,3,5-triaryl-4-alkylpyrazolines and -pyrazoles by treatment of α-benzotriazolyl-α,β-unsaturated ketones withmonosubstituted hydrazines followed by alkylation at the 4-position of the pyrazoline ring. Reactionof α-benzotriazolyl-α,β-unsaturated ketones with hydroxylamine gives 3,5-disubstituted isoxazolesregioselectively.
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