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À propos de : Application of2-(3,5,6-Trifluoro-2-hydroxy-4-methoxyphenyl)benzoxazole and-benzothiazole to Fluorescent Probes Sensing pH and MetalCations        

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  • Application of2-(3,5,6-Trifluoro-2-hydroxy-4-methoxyphenyl)benzoxazole and-benzothiazole to Fluorescent Probes Sensing pH and MetalCations
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  • 2-(3,5,6-Trifluoro-2-hydroxy-4-methoxyphenyl)benzoxazole (3) and benzothiazole analogue (4) areprepared by the two-step procedures from the corresponding 2-(pentafluorophenyl)benzazoles.Benzoxazole 3 is applicable to a fluorescent probe sensing magnesium cation, and 4 is suitable forsensing zinc cation. Both fluorophores 3 and 4 are sensitive to the pH change at pH 7−8, resultingin large fluorescence enhancement under basic conditions. Their high sensitivity to pH andselectivity in metal cations are ascribed to the high acidity of the fluorophenol moiety.
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