| Abstract
| - The 1,4-addition of primary alcohols, higher nitroalkanes, and a Schiff's base of an α-amino esterto α,β-unsaturated substrates produces the corresponding products in moderate to excellent yieldswhen carried out at −63 to 70 °C in the presence of catalytic amounts of the nonionic strong basesP(RNCH2CH2)3N (R = Me, i-Pr, i-Bu) in isobutyronitrile. Diastereoselectivity for the anti form ofthe product is high in the case of the Schiff's base in the absence of lithium ion. These catalysts areeasily removed from the product by either column filtration through silica gel or via aqueous workup.
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