Abstract
| - A stereoselective Julia−Lythgoe olefination has allowed the first total synthesis of A2 isoprostane(1), a recently discovered member of the growing isoprostane family. This elusive compound opensup numerous new avenues for the molecular biology of cyclopentenone prostaglandins, which areendowed of intriguing biological effects such as antitumor, antiinflammatory, and antiviral activities.
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