Abstract
| - Acyclic and cyclic acetals of various carbonylcompounds were obtained in excellent yields under a mildreaction condition in the presence of trialkyl orthoformateand a catalytic amount of tetrabutylammonium tribromide(TBATB) in absolute alcohol. Chemoselective acetalizationof an aldehyde in the presence of ketone, unsymmetricalacetal formation, shorter reaction times, mild reactionconditions, the stability of acid-sensitive protecting groups,high efficiencies, facile isolation of the desired products, andthe catalytic nature of the reagent make the presentmethodology a practical alternative.
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