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À propos de : Synthesis of the C1‘−C11‘Oxazole-Containing Side Chain ofLeucascandrolide A. Application of aSonogashira Cross-Coupling        

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  • Synthesis of the C1‘−C11‘Oxazole-Containing Side Chain ofLeucascandrolide A. Application of aSonogashira Cross-Coupling
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  • An efficient, convergent synthesis of theC1‘−C11‘ side chain (3) of leucascandrolide A (1) has beenachieved. The key bond connection is made through the useof a palladium(0)-catalyzed Sonogashira cross-coupling between trifloyl oxazole (4) and alkynylmetal species (5).
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