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À propos de : Synthesis of New Molecules Containing Head, Spacer, and LabelMoieties        

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  • Synthesis of New Molecules Containing Head, Spacer, and LabelMoieties
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  • We describe the synthesis and characterization of novel molecules containing head with preciseshape, spacer, and label moieties. The protocol is based on a Pd(0)-catalyzed cross-coupling reactionbetween ethynylphenyl/bromide to obtain a rigid head followed by the attachment of a flexiblespacer possessing two reactive functional groups on the termini. The final step consists of forminga covalent bond between spacer and label. In addition, monosubstituted soluble labels weresynthesized in good yields.
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