| Abstract
| - Ionic liquid-coated enzyme (ILCE) is describedas a useful catalyst for biocatalysis in organic solvent. Anionic liquid, [PPMIM]-[PF6] (1, [PPMIM] = 1-(3‘-phenylpropyl)-3-methylimidazolium), which is solid at room temperature and becomes liquid above 53 °C, was synthesized intwo steps from N-methylimidazole. The coating of enzymewas done by simply mixing commercially available enzymewith 1 in the liquid phase above 53 °C and then allowingthe mixture to cool. A representative ILCE, prepared witha lipase from Pseudomonas cepacia, showed markedlyenhanced enantioselectivity without losing any significantactivity.
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