About: Synthesis of Enantiopure Cis- andTrans-2,3-Disubstituted Piperidines

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Attributs	Valeurs
type	work Article
Is Part Of	http://hub.abes.fr/acs/periodical/joceah/2002/volume_67/issue_21/w
Subject	Note
Title	Synthesis of Enantiopure Cis- andTrans-2,3-Disubstituted Piperidines
has manifestation of work	http://hub.abes.fr/acs/periodical/joceah/2002/volume_67/issue_21/101021jo025955/m/print http://hub.abes.fr/acs/periodical/joceah/2002/volume_67/issue_21/101021jo025955/m/web
related by	http://hub.abes.fr/acs/periodical/joceah/2002/volume_67/issue_21/101021jo025955/authorship/1 http://hub.abes.fr/acs/periodical/joceah/2002/volume_67/issue_21/101021jo025955/authorship/2 http://hub.abes.fr/acs/periodical/joceah/2002/volume_67/issue_21/101021jo025955/authorship/3 http://hub.abes.fr/acs/periodical/joceah/2002/volume_67/issue_21/101021jo025955/authorship/4
Author	Dechoux Luc Hebbe Séverine Agami Claude Ménard Cécilia
Abstract	The synthesis of enantiopure cis- and trans-2,3-disubstituted piperidines 4 is described. The key step of thesynthesis involves the stereoselective reduction of chiralnonracemic lactams 2 by using BH3·Me2S. A rationalizationof the stereoselectivity is presented.
article type	brief-report
is part of this journal	The Journal of Organic Chemistry

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