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À propos de : An Efficient Synthesis ofPyrrolo[2,3-d]pyrimidines via InverseElectron Demand Diels−Alder Reactions of2-Amino-4-cyanopyrroles with1,3,5-Triazines        

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  • An Efficient Synthesis ofPyrrolo[2,3-d]pyrimidines via InverseElectron Demand Diels−Alder Reactions of2-Amino-4-cyanopyrroles with1,3,5-Triazines
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  • The scope of the inverse electron demand Diels−Alder reaction of 2-amino-4-cyanopyrroles (3a−e) with 1,3,5-triazines (1, 2) is reported. This methodology is suitable forone-pot syntheses of highly substituted and highly functionalized pyrrolo[2,3-d]pyrimidines that are the central heterocyclic nucleus of various nucleoside natural products suchas toyocamycin, sangivamycin, and tubercidin.
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