| Abstract
| - The first nickel-catalyzed cross-coupling reactions between fluoroarenes and aryl organometallicsusing commercially available ligands are described. The nickel-catalyzed cross-coupling reactionsbetween aryl Grignard reagents and fluoroazines and -diazines occurred in THF at roomtemperature using commercially available 1,2-bis(diphenylphosphino)ethane, 1,3-bis(diphenylphosphino)propane, or 1,1‘-bis(diphenylphosphino)ferrocene as ligand. Various fluoro substrates suchas pyridines, diazines (pyrazine, pyridazine), benzodiazines (quinoxaline), and quinolines weresuccessfully involved in the reaction with phenylmagnesium halides (phenylmagnesium chloride,2-methoxyphenylmagnesium bromide, and 4-methoxyphenylmagnesium bromide). The conditionsused also allowed the cross-coupling of 4-fluorotoluene with arylmagnesium reagents.
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