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À propos de : Total Synthesis of (−)-Callystatin A        

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  • Total Synthesis of (−)-Callystatin A
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  • A total synthesis of the cytotoxic polyketide marine natural product callystatin A is described. Theroute features chiral allenylmetal additions to construct the polypropionate C15−22 segment andan sp2−sp3 Suzuki coupling to join the C1−C11 and C12−C22 subunits.
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