| Abstract
| - On the basis of our previously described selectiveprotection of arabitol as its 1,2:4,5-bis-pentylidene acetal 5,we report a straightforward synthesis of the novel “pseudo”-C2-symmetric 3-azido-1,2:4,5-diepoxypentane building block4 in 6 steps from arabitol. Using a similar synthetic route,an improved synthesis of the C2-symmetrical 1,2:4,5-bis-epoxypentane building block 1 is described, also in 6 stepsfrom arabitol. Both enantiomers of 1 and 4 are accessible,and all reactions involved are easily amenable for large-scalesynthesis.
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