| Abstract
| - The amino−zinc−ene−enolate cyclization reaction is a straightforward route to the synthesis of3-substituted prolines. Herein we report the application of this reaction to the syntheses of prolinechimeras of lysine, glutamic acid, glutamine, arginine, and serine. All these compounds wereobtained in enantiomerically pure form and suitably protected for peptide synthesis.
|
