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  • An Investigation of the Reaction of 2-AminobenzaldehydeDerivatives with Conjugated Nitro-olefins: An Easy and EfficientSynthesis of 3-Nitro-1,2-dihydroquinolines and 3-Nitroquinolines
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  • 2-Aryl-3-nitro-1,2-dihydroquinolines 3 were prepared from the reaction of β-nitrostyrenes 2 and2-aminobenzaldehyde 1 in the presence of DABCO. Not only β-nitrostyrenes but other alkyl nitroolefins also can be used in this reaction as well. When DDQ or silica gel was added to a solution of3-nitro-1,2-dihydroquinolines 3, 3-nitro-2-substituted-quinolines 4 were obtained. When 2-aminobenzaldehyde derivatives 7 and 12 were reacted with β-nitrostyrenes 2, unique rearrangementproducts were produced.
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