| Abstract
| - The enantioselective catalytic 1,4-addition to α,β-unsaturated ketimines is an unprecedented process. Herein, wedocument the copper-catalyzed addition of dialkylzinc reagents to (2-pyridylsulfonyl)imines of chalcones. This processoccurs rapidly in the presence of a chiral phosphoramiditeligand to afford exclusively the 1,4-addition product. In thecase of addition of dimethylzinc, enantioselectivities in therange 70−80% ee are obtained. The presence of the metal-coordinating 2-pyridylsulfonyl group proved to be essentialfor this reaction to proceed.
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