About: One-Pot Copper(I)-Catalyzed Synthesis of3,5-Disubstituted Isoxazoles

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Attributs	Valeurs
type	work Article
Is Part Of	http://hub.abes.fr/acs/periodical/joceah/2005/volume_70/issue_19/w
Subject	Note
Title	One-Pot Copper(I)-Catalyzed Synthesis of3,5-Disubstituted Isoxazoles
has manifestation of work	http://hub.abes.fr/acs/periodical/joceah/2005/volume_70/issue_19/101021jo050163b/m/print http://hub.abes.fr/acs/periodical/joceah/2005/volume_70/issue_19/101021jo050163b/m/web
related by	http://hub.abes.fr/acs/periodical/joceah/2005/volume_70/issue_19/101021jo050163b/authorship/1 http://hub.abes.fr/acs/periodical/joceah/2005/volume_70/issue_19/101021jo050163b/authorship/2 http://hub.abes.fr/acs/periodical/joceah/2005/volume_70/issue_19/101021jo050163b/authorship/3
Author	Fokin Valery V. Hansen Trond V. Wu Peng
Abstract	3,5-Disubstituted isoxazoles are obtained in good yields bya convenient one-pot, three-step procedure utilizing a regioselective copper(I)-catalyzed cycloaddition reaction betweenin situ generated nitrile oxides and terminal acetylenes.Most functional groups do not interfere with the reaction,which can be performed in aqueous solvents without protection from oxygen. Since all reagents are used in stoichiometric amounts, formation of byproducts is minimized.
article type	brief-report
is part of this journal	The Journal of Organic Chemistry

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