| Abstract
| - A boron-mediated syn- and anti-stereoselective aldol reaction giving rise to various β-hydroxyenoneswas coupled to a Pd(II)-mediated oxidative cyclization to give 2,3,6-trisubstituted syn- and anti-dihydropyranones in good yields. The Pd(II)-mediated oxidative cyclization was expanded toα-hydroxyenones leading to furan-3(2H)-one derivatives, which include natural product bullatenoneand a known precursor of geiparvarin. The sole product of the oxidative cyclization of α,β-dihydroxyenone was a five-membered furan-3(2H)-one derivative, suggesting that the ring closureof these diols is both chemo- and regioselective.
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