Abstract
| - An efficient kinetic resolution of racemic Betti base withl-(+)-tartaric acid in acetone was developed based on a novelenantioselective N,O-deketalization, by which the enantiopure R- and S-enantiomers of Betti base were obtainedas the corresponding N,O-ketal compound and salt withl-(+)-tartaric acid, respectively, in excellent yields with apractically foolproof operation.
|