| Abstract
| - A versatile, efficient, and simple method for the preparationof various 1-chloroethyl phosphates and phosphoramidatesis described. The protected chlorophosphates or phosphoramidates are synthesized to the vinyl derivative under mildconditions, followed by conversion to the chloroethylidenephosphate or phosphoramidate by dry HCl gas, resulting ingood to excellent yields. 1-Chloroethyl phosphates andphosphoramidates are excellent building blocks for thesynthesis of novel ethylidene-linked phosphate prodrugs.
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