A series of novel chiral ionic liquids (CILs) has beensynthesized and fully characterized. The reaction of 1-methyl-2-imidazolecarboxaldehyde and chiral amino alcoholsfollowed by reduction is key to the design of these new CILs.This is the first time that CILs have been synthesized byintroducing chiral scaffolds on the C-2 position of theimidazolium cation of ILs. The simple and straightforwardprocedure resulted in CILs as colorless oils at room temperature in good yields.