| Abstract
| - Five 1-benzazepine heterocycles were synthesized by utilizing transition-metal-catalyzed processesin key bond-forming steps. exo-Methylene and methyl substituents were introduced at position 5,as well as a unit of unsaturation between positions 3 and 4, with benzoyl or benzyl N-substituents.Solution- and solid-state structures were examined, using dynamic NMR spectroscopy and X-raycrystallography, corroborated by molecular mechanics calculations. Greater amide distortion isassociated with a more stable ground-state structure, which is in turn more reluctant to undergoconformational changes.
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