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À propos de : Nickel-Catalyzed Cyclization of 2-Iodoanilineswith Aroylalkynes: An Efficient Route forQuinoline Derivatives        

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  • Nickel-Catalyzed Cyclization of 2-Iodoanilineswith Aroylalkynes: An Efficient Route forQuinoline Derivatives
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  • An efficient and convenient nickel-catalyzed cyclization of2-iodoanilines with alkynyl aryl ketones to give 2,4-disubstituted quinolines was developed. The reaction can beemployed for the synthesis of naturally occurring quinolinederivatives in good yields. On the basis of the regiochemistryof the products, the possible pathway for the reaction is viathe formation of o-aminochalcone.
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