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À propos de : Molecular Recognition: Improved Binding of Biotin Derivativeswith Synthetic Receptors        

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  • Molecular Recognition: Improved Binding of Biotin Derivativeswith Synthetic Receptors
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  • NMR titrations and Monte Carlo conformational searches have been used to study the molecular recognitionfeatures of five urea derivatives with two synthetic hosts. We have improved the binding constant (Kb)values for all the studied guests and measured the largest binding constant of a complex involving abiotin derivative (biotin methyl ester) bound to a synthetic host by means of several interaction pointsand not only through the urea moiety.
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