| Abstract
| - A straightforward method for the synthesis of original 4,4-dialkoxy- or 4,4-diaryloxy-diaza-s-indacenes (BODIPY)derivatives obtained by treatment of BODIPY 1 with variousalcohols in the presence of AlCl3 is described. The novelcompounds are characterized by spectroscopic propertiessimilar to those of the parent BODIPY 1, absorption andemission spectra with similar band shapes, high molarabsorption coefficients (ελmax ≈ 80 000 M-1 cm-1), and formost of them high fluorescence quantum yields (Φexp from0.52 to 0.71). Among all of the new compounds synthesized,the dye 2h exhibits higher fluorescence quantum yield (0.71)and lifetime (4.09 ns) than compound 1 and a good chemicalstability toward conditions compatible with biological cell-based assays.
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