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À propos de : Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-,12-, and 16-Membered Macrocyclic Scaffolds: Synthesis andAggregation Study        

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  • Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-,12-, and 16-Membered Macrocyclic Scaffolds: Synthesis andAggregation Study
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  • Bis- and trisuracil nucleosides, in which the nucleobases are anchored to isoxazoline ring-fused 11-, 12-,and 16-membered macrooxacycles, were synthesized by nucleosidation of 1,2-isopropylidenefuranosering-fused macrocycles. The nucleosides exhibited spherical and fiber-like morphologies in water. Inone case, the morphology was significantly altered by complexation with an adenine nucleoside viacomplementary base pairing.
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