Abstract
| - Reaction of 2-substituted dienamides with catalytic amountsof copper halide/tripyridylamine (TPA) furnishes either 5-exoor 6-endo products with the outcome dependent upon theradical initiating unit. Reaction of 3-substituted dienamidesproduces β-lactams via a 4-exo cyclization with terminationof the reaction occurring via either halogen atom transfer,trapping with oxygen, elimination, or radical−radical coupling depending upon the diene.
|