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À propos de : Et2Zn-Catalyzed Intramolecular Hydroamination of AlkynylSulfonamides and the Related Tandem Cyclization/AdditionReaction        

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  • Et2Zn-Catalyzed Intramolecular Hydroamination of AlkynylSulfonamides and the Related Tandem Cyclization/AdditionReaction
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  • Intramolecular hydroamination of alkynyl amides was effected by a catalytic amount of Et2Zn (20 mol%) to form indole derivatives, and a tandem cyclization/nucleophilic addition procedure involving reactionof the indole zinc salt intermediate with acid chlorides or halides was developed to provide an efficientapproach to C3-substituted indole derivatives when an excess of Et2Zn (120 mol %) was used.
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