| Abstract
| - A complete E-selective synthesis of α,β-unsaturated amides through a sequential reaction of a range ofdichloroamides with a variety of aldehydes promoted by Rieke manganese (Mn*) is reported. A mechanismbased on a sequential aldol-type reaction and a completely stereoselective β-elimination is proposed toexplain these results. The unsaturated amides obtained are readily and efficiently transformed into α,β-unsaturated ketones, aldehydes, or carboxylic acids without loss of the diastereoisomeric purity of theC−C double bond.
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