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À propos de : Absolute Configuration of Myrobotinol, NewFused-Hexacyclic Alkaloid Skeleton fromMyrioneuron nutans        

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  • Absolute Configuration of Myrobotinol, NewFused-Hexacyclic Alkaloid Skeleton fromMyrioneuron nutans
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  • Myrobotinol (1) was isolated from the leaves of Myrioneuronnutans (Rubiaceae) and its structure determined from spectraldata, including mass spectrometry and 2D NMR. Thiscompound presents a new hexacyclic alkaloid skeletonincluding a 1,3-oxazine and aminal functionality. Theabsolute configuration of myrobotinol was established byusing Mosher's method. A plausible biosynthetic pathwaystarting from l-lysine via Δ-piperideine was proposed forthis hexacyclic alkaloid.
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