An efficient FeCl3-catalyzed substitution reaction of propargylic acetates with enoxysilanes under mild conditions toafford corresponding γ-alkynyl ketones has been developed.The substitution reaction is followed by a TsOH-catalyzedcyclization without purification of the γ-alkynyl ketoneintermediates, offering a straightforward synthetic route totri- or tetrasubstituted furans.