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À propos de : New Approach to the Synthesis of MacrocyclicTetralactones via Ring-Closing Metathesis UsingGrubbs' First-Generation Catalyst        

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  • New Approach to the Synthesis of MacrocyclicTetralactones via Ring-Closing Metathesis UsingGrubbs' First-Generation Catalyst
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  • A facile and efficient route to synthesize macrocyclictetralactones with different ring sizes having a wide varietyof spacers is described. The application of ring-closingmetathesis for the synthesis of macrocyclic tetralactones isdemonstrated with many examples in excellent yield. Therepresentative structure of macrocyclic tetralactones ischaracterized by X-ray crystallography.
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