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À propos de : Copper-Catalyzed Double N-Alkenylation ofAmides: An Efficient Synthesis of Di- orTrisubstituted N-Acylpyrroles        

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  • Copper-Catalyzed Double N-Alkenylation ofAmides: An Efficient Synthesis of Di- orTrisubstituted N-Acylpyrroles
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  • An efficient copper-catalyzed double alkenylation of amideswith (1Z,3Z)-1,4-diiodo-1,3-dienes is reported for the firsttime. The reactions proceed to afford di- or trisubstitutedN-acylpyrroles in good to excellent yields using CuI as thecatalyst, Cs2CO3 as the base, and rac-trans-N,N‘-dimethylcyclohexane-1,2-diamine as the ligand.
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