| Abstract
| - 2-(Methoxymethoxymethyl)aryllead triacetates, obtained in situ from the corresponding arylboronic acids,reacted with 4-hydroxycoumarins, leading to 3-(2-methoxymethoxymethyl)aryl-4-hydroxycoumarinderivatives in good to high yields. These compounds underwent a cascade sequence of reactions,deprotection−halogenation−annulation, to afford polyoxygenated tetracyclic 6H,11H-[2]benzopyrano-[4,3-c] [1]benzopyran-11-ones in good yields. Some compounds showed a moderate cytotoxicity againsthuman epithelial mammary HBL100 cells.
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