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À propos de : Efficient Access to 2-Isobetulinic Acid, 2-Isooleanolic Acid, and 2-Isoursolic Acid        

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  • Efficient Access to 2-Isobetulinic Acid, 2-Isooleanolic Acid, and 2-Isoursolic Acid
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  • An efficient access to 2-isobetulin, 2-isobetulinic acid, 2-isooleanolic acid, and 2-isoursolic acid has been developed. The key step is a novel one-pot conversion of 2,3-dihydroxy triterpenes to 3-deoxy-2-oxo triterpenes. This method provides a new access to 3-deoxy-2-substituted pentacyclic triterpenes as potential therapeutic agents against metabolic diseases, tumors, and HIV infection.
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