| Abstract
| - The global electrophilicity pattern of singlet carbenes has been evaluated using an absolute scale based onreactivity indexes and an extension of it to describe the local electrophilicity power of molecules. The predictedelectrophilicity values agree well with the relative experimental scale, based on kinetic data proposed byMoss [Acc. Chem. Res.1989, 22, 15]. A good qualitative comparison is found between the theoretical andexperimental carbene-philicity. The theoretical model is able to accommodate within a unique scale thosecarbenes evaluated as electrophilic, ambiphilic, and nucleophilic species. The local analysis provides additionalinformation about electrophilic activation/deactivation patterns induced by substituent groups in the molecule.
|
