| Abstract
| - Mixed micelles of solubilized dimyristoyl phosphatidylcholine (DMPC) and the zwitterionic detergentdodecyldimethylammoniopropane sulfonate are characterized employing time-resolved fluorescence quenching(TRFQ), electron spin resonance (ESR), and surface tensiometry toward the goal of investigating interfacialreactions using these micelles as host reaction media. The properties measured are the micelle aggregationnumbers, interfacial hydration index, microviscosity, and the critical micelle concentrations for various molarfractions, XDMPC, of DMPC, 0 ≤ XDMPC< 0.35. A complementary interpretation of the experimental resultsfrom TRFQ and ESR within the framework of a polar shell model for the mixed micelle yields somemicrostructural features, including the micelle core radius, polar shell thickness, and the fraction of the totalhydrocarbon that overlaps with the micelle−water interface. The results of the characterization are applied ininvestigating an interfacial reaction; namely, micellar fluorescence quenching. A bulk hydrodynamic modelwhen modified appropriately so as to be applicable to reaction within the interface is shown to describemicellar fluorescence quenching kinetics and also provides some insight into the location of guest moleculesin micelles.
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