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À propos de : Violation of Distribution Symmetry in Statistical Evaluation of Absolute EnantioselectiveSynthesis        

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  • Violation of Distribution Symmetry in Statistical Evaluation of Absolute EnantioselectiveSynthesis
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  • Enantiomeric excesses obtained in absolute enantioselective synthesis by chiral autocatalysis (Soai-reaction)were statistically analyzed. Two sets of parallel experiments, which were performed under chemically differentconditions, are available. One group contains 37, while the other contains 84 preparative results. The formergroup shows some interesting tendencies but does not give conclusive statistical results. The sample of 84parallel experiments, providing 39 R- and 45 S-excesses have shown that these data represent two distinct,non-symmetric sets with different non-Gaussian distributions. Clear S preference was found.
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