| Attributs | Valeurs |
|---|
| type
| |
| Is Part Of
| |
| Subject
| |
| Title
| - Coarse-graining the Self-assembly of β-helical Protein Building Blocks
|
| has manifestation of work
| |
| related by
| |
| Author
| |
| Abstract
| - Nanotubular structures constructed using self-assembled β-helical protein building blocks one atop the otherhave been coarsened to develop a mesoscopic potential that reproduces the intermolecular interaction energiesprovided by atomistic force-fields. The resulting potential consists of an analytical expression that dependsexclusively on the distance and the relative orientation between the two interacting entities. In spite of itscomplexity, this coarse-grained potential reproduces satisfactorily the energetic properties of two interactingbuilding blocks. The coarse-grained potential has been used to predict that the interaction between buildingblocks formed by residues 131−165 of E. coli galactoside acteyltransferase becomes repulsive when the sizeof the nanotube is larger than a threshold, that is, about 45 self-assembled building blocks.
|
| article type
| |
| is part of this journal
| |
