| Abstract
| - High-stability sensing of proteins of pig serum albumin (PSA) was achieved using an insulator-covered carbon-nanotube field-effect transistor (CNT-FET) with a top-gate structure. The sensitivity limit of this CNT-FETPSA sensor is at least 5 nmol/L PSA solution. A layer of silicon nitride deposited on the top-gate structureprovides an n-type characteristic and a highly stable CNT-FET. Since the CNT is covered with a siliconnitride layer, it is isolated from oxygen, water, and other contaminants. The equilibrium constant of the PSA/anti-PSA reaction, which indicates the strength of the binding energy between PSA and anti-PSA fixed onthe Au top-gate electrode, was calculated to be 1.2 × 107 L/mol using the Langmuir equation fitting.
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