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À propos de : Transmembrane-Peptide-Induced Clustering ofPhospholipids        

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  • Transmembrane-Peptide-Induced Clustering ofPhospholipids
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  • Experimental evidence has been obtained for the transmembrane-peptide-induced clustering ofphospholipids in the fluid bilayer state by use of the nearest-neighbor recognition method. Specifically,the exchangeable phospholipid monomers of 1a and 1b were found to mix, apparently, nonideally andcooperatively in liposomal membranes containing 9 mol % of the nonchannel form of gramicidin A.Equilibrium dimer distributions that were measured as a function of the initial ratio of 1a/1b support amodel in which discrete clusters are formed that contain two molecules of 1b.
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