| Abstract
| - The first diiron thiadithiolates as active site models for the Fe-only hydrogenases were prepared.Treatment of Fe3(CO)12 with excess 1,2,4-trithiolane in THF at reflux afforded parent model Fe2(μ-SCH2)2S(CO)6 (1) in 42% yield. Further treatment of 1 with Cp(CO)2Fe(BF4) prepared in situ fromCp(CO)2FeI and AgBF4 in CH2Cl2 gave cationic model [Fe2(μ-SCH2)2S(CO)6][Cp(CO)2Fe](BF4) (2) in81% yield, while treatment of 1 with 2 equiv of Et4NCN in MeCN or with t-BuNC in CH2Cl2 producedmodels (Et4N)2[Fe2(μ-SCH2)2S(CO)4(CN)2] (3) and Fe2(μ-SCH2)2S(CO)4(t-BuNC)2 (4) in 93% and 51%yields, respectively. All the new models 1−4 were characterized by elemental analysis and spectroscopy,as well as by X-ray crystallography for 1, 2, and 4. Furthermore, model 1 has been proved to be acatalyst for proton reduction of a weak acid Et3NHCl to give hydrogen under electrochemical conditions.
- The first diiron thiadithiolates as biomimetic models 1−4 were synthesized and structurally characterized. In addition, model 1 has been proved to be a catalyst for reduction of proton to hydrogen under electrochemical conditions.
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