Documentation scienceplus.abes.fr version Bêta

À propos de : Continuous midazolam infusion as treatment of status epilepticus        

AttributsValeurs
type
Is Part Of
Subject
Title
  • Continuous midazolam infusion as treatment of status epilepticus
has manifestation of work
related by
Abstract
  • In a tertiary referral centre, midazolam infusion was tried as treatment for 20 children with status epilepticus over a period of two years. The mean age of the children was 4.07 years. Twelve children with refractory status epilepticus had received intravenous or per rectal diazepam and intravenous phenytoin/phenobarbitone or both before midazolam was given (0.15 mg/kg bolus followed by 1-5 μg/kg/min infusion). Eight children required only midazolam to control the established status epilepticus. The seizures were controlled in 19 children. The mean time required for complete cessation of seizures was 0.9 hours. The mean infusion rate required was 2.0 μg/kg/min. All children had regained full consciousness by a mean of 5.1 hours after discontinuation of midazolam treatment. No metabolic derangement or compromise of vital functions was noted in any of the children. Midazolam infusion is thus an effective and safe therapeutic approach for the management of childhood status epilepticus.
article type
publisher identifier
  • 96398
is part of this journal
PubMed ID
  • 9196363



Alternative Linked Data Documents: ODE     Content Formats:       RDF       ODATA       Microdata