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Evidence in context: one person’s poison is another’s acceptable risk
Review: postmenopausal hormone therapy increases risk of stroke and venous thromboembolism but not coronary heart disease events
A combination of telmisartan and ramipril increased renal outcomes in vascular disease or diabetes
The San Francisco Syncope Rule did not accurately predict serious short-term outcome in patients with syncope
Review: faecal occult blood test screening reduces risk of colorectal cancer mortality
The Paediatric Appendicitis Score (PAS) was useful in children with acute abdominal pain
Benefits of early intensive glucose control to prevent diabetes complications were sustained for up to 10 years
The Splenoportal Index accurately predicted the presence of oesophageal varices in compensated cirrhosis
Other articles noted
Benefits of tight blood pressure control to prevent diabetes complications were not sustained
Delayed antibiotics for children with acute otitis media: is practice change sustainable?
CD4+ count-guided antiretroviral therapy interruption increased opportunistic disease and death more than continuous therapy in HIV
Letter: self-monitoring of blood glucose—caution warranted
Review: vasomotor symptoms peak at 1 year after final menstrual period and may persist for many years
Additional articles abstracted in ACP Journal Club
Review: daily salmeterol increases non-fatal serious adverse events in chronic asthma
Resource reviews
Practice corner: should we screen all patients starting chemotherapy for chronic hepatitis B virus infection?
Review: medication adjustment based on fractional exhaled nitric oxide did not prevent asthma exacerbations
Jottings....
Review: people with epilepsy have higher risk of death by drowning than the general population
Glossary
Purpose and procedure
Alexander technique lessons were effective for chronic or recurrent back pain at 1 year
Review: an early invasive strategy has similar benefits in men and women with NSTEMI or unstable angina
A single measure of urinary neutrophil gelatinase-associated lipocalin was accurate for diagnosing acute kidney injury
General practitioners’ advice to use topical rather than oral ibuprofen resulted in equivalent effects on chronic knee pain
Resource reviews
Physician training in the use of a decision aid increased patient participation in decision making for CVD prevention
Evidently…
Resource reviews
Excess mortality after HIV seroconversion has greatly decreased in the past 10 years
Active management of risk in pregnancy at term did not reduce caesarean delivery rates
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