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While hormone therapy unlikely harmful in younger postmenopausal women at low CV risk, protective effects cannot be claimed
Use of cranberry products does not appear to be associated with a significant reduction in incidence of recurrent urinary tract infections
Tiotropium bromide triple combination therapy improves lung function and decreases asthma exacerbations
The possible effects of depressive symptoms on risk of preterm birth are clouded by lack of control over confounding factors
Screening for type 2 diabetes does not reduce mortality over 10 years
Antibiotics are not beneficial for patients with clinically diagnosed uncomplicated acute rhinosinusitis
Need remains for evidence-based reassurance for absence of bilirubin neurotoxicity with severe hyperbilirubinaemia
Opinion editorials: the science and art of combining evidence with opinion
Children gain less weight and accumulate less fat when sugar-free, non-caloric beverages are substituted for sugar-sweetened beverages
After a negative screening colonoscopy, a microsimulation model shows that currently recommended strategies are equally effective for rescreening
Women whose cervical intraepithelial neoplasia has been treated or resolved remain at continued high risk for cervical cancer
Opioid substitution therapy is associated with decreased HIV transmission among people who inject drugs
Use of psychotropic medication in Alzheimer's disease is associated with more rapid cognitive and functional decline
Currently available smartphone apps for asthma have worrying deficiencies
How to confidently teach EBM on foot: development and evaluation of a web-based e-learning course
Topical NSAIDS provide effective pain relief for patients with hand or knee osteoarthritis with similar efficacy, and fewer side effects, than oral NSAIDS
Exenatide may improve maintenance of HbA1c targets, with less hypoglycaemia, but more early adverse effects when compared with low-dose glimepiride
Statins in patients with CKD prove beneficial in reducing cardiovascular events and mortality but show no benefit in patients on dialysis
Child poisonings are more common in households experiencing psychosocial stressors
Prophylactic antiretroviral HIV therapy prevents infection in heterosexual men and women
Pretest probability assessment combined with point-of-care D-dimer testing allows primary care physicians to rule out pulmonary embolism
Proton pump inhibitor use may be associated with an increased risk of Clostridium difficile infection
Ambulatory test result follow-up represents a serious problem and solutions are needed
Nucleic acid amplification tests of self-taken vulvovaginal swabs are more sensitive than clinician taken endocervical culture for gonorrhoea
Montelukast potentially efficacious in children with non-severe obstructive sleep apnoea in the short term
Proton pump inhibitors do not induce change in bone mineral density in a long-term observational study
Muscle strength during adolescence is associated with longevity
Individual patient data meta-analysis of diagnostic studies: opportunities and challenges
It is still an open question whether inhaled glucocorticoid-induced effects may reduce adult height
Unclear whether energy-based vessel sealing in vaginal hysterectomy is superior to conventional clamping and suturing
Network meta-analysis shows that prostaglandin inhibitors and nifedipine are best short-term tocolytics for preterm delivery
Vaccination of older adults against herpes zoster is safe and effective
Compression-only CPR may improve survival for patients in cardiac arrest due to shockable rhythms treated by bystanders with public access defibrillation
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