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The EPOS prediction model improves ability to predict transition to first episode psychosis in individuals at high risk
High mortality and reduced quality of life in people who have presented to hospital for self-harm in the UK
Compared with fluoxetine monotherapy, mirtazapine plus venlafaxine or fluoxetine increase remission but not response in patients with major depressive disorder
Second generation antipsychotics are not superior in relieving family burden in schizophrenia compared with the first generation antipsychotic perphenazine
Purpose and procedure
Evidence based mental health and Web 2.0
Antipsychotic polypharmacy is not associated with increased mortality from natural causes in patients with schizophrenia compared to monotherapy
Angiotensin receptor blockers associated with decreased incidence and progression of dementia in older men with cardiovascular disease
Injectable diacetylmorphine is more effective than oral methadone in the treatment of chronic relapsing opioid dependence
Quetiapine is effective in the treatment of adults in the acute phase of bipolar depression
Binge drinking frequent among adults aged 50 years and older
Past or current drug or alcohol use disorders increase the likelihood of a switch from depressive to manic, mixed or hypomanic states in patients with bipolar disorder
Cholinesterase inhibitor treatment may double the risk of hospitalisation for bradycardia
Review: befriending modestly reduces depressive symptoms in varied populations
Bifrontal, bitemporal and right unilateral ECT electrode placement are similarly effective for reducing depressive symptoms
Glossary
Extremely preterm children at increased risk of autism spectrum disorders
Review: ADHD impairs quality of life, but children and young people with ADHD perceive less impairment than parents
A GP training package for the treatment of anxiety disorders is not cost-effective
Review: evidence on the effect of antiepileptics on recurrent aggression inconclusive
Moderate or high physical activity lowers the risk of cognitive impairment in older people
Current use of venlafaxine not associated with excess risk of sudden cardiac death or near death compared with fluoxetine, citalopram or dosulepin
Misconceptions about gene-environment interactions in psychiatry
Brief, personality-targeted coping-skills intervention reduces onset and escalation of drug misuse
A stepped care programme for depressive or anxiety disorders offers good value for money
Review: exercise programmes reduce anxiety symptoms in sedentary patients with chronic illnesses
Escitalopram may improve some cognitive functions after stroke in non-depressed patients
The PHQ-9 works well as a screening but not diagnostic instrument for depressive disorder
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