About: Chronic valproic acid intoxication: reversal by naloxone

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Attributs	Valeurs
type	work Article
Is Part Of	http://hub.abes.fr/bmj/periodical/emermed/2007/volume_24/issue_9/w
Subject	Emergency casebooks
Title	Chronic valproic acid intoxication: reversal by naloxone
has manifestation of work	http://hub.abes.fr/bmj/periodical/emermed/2007/volume_24/issue_9/B355DAF4DC4756D4E053120B220AAEEF/m/web http://hub.abes.fr/bmj/periodical/emermed/2007/volume_24/issue_9/B355DAF4DC4756D4E053120B220AAEEF/m/print
related by	http://hub.abes.fr/bmj/periodical/emermed/2007/volume_24/issue_9/B355DAF4DC4756D4E053120B220AAEEF/authorship/1
Abstract	A 76-year-old woman being treated with sodium valproate for bipolar depression presented with a 4 day history of acute confusion and tremulousness. She had apnoeic episodes, reduced conscious level and generalised myoclonic movements. Her plasma valproate concentration was 848 µmol/l (normal 300-600 µmol/l). Administration of naloxone 0.8 mg led to rapid clinical improvement. Naloxone may be useful in reversing the features of chronic valproate toxicity.
article type	other
is part of this journal	Archives of Emergency Medicine
PubMed ID	17711961

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