| Abstract
| - Black hypertensive diabetics have been shown to exhibit elevated intracellular calcium which may stimulate Na/H antiport. Since Na/Li countertransport appears to be a functional mode of Na/H antiport, we measured erythrocyte Na/Li countertransport in nondiabetic normotensive and hypertensive blacks and whites and hypertensive noninsulin-dependent diabetic blacks. Na/Li countertransport was significantly lower in the blacks than in the whites (0.170 ± 0.017 + 0.230 ± 0.017 mmol/L/h, P< .02), but there was no significant difference between the black hypertensives and normotensives. In contrast, black hypertensive diabetics exhibited a significant increase in Na/Li countertransport compared to normotensive and hypertensive nondiabetic blacks (0.252 ± 0.032 ν 0.170 ± 0.017, P< .02. Thus, these data indicate that the activity of this antiporter is elevated in black diabetics, possibly further contributing to the development of hypertension in this population. Am J Hypertens 1990;3:563-565.
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