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| - Systolic thickening increases from subepicardium to subendocardium
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| - Study objective - The aim was to determine the relation between systolic function and depth below the epicardial surface, using pulsed Doppler crystals. Design - Systolic excursion in mm was measured at multiple depths below the epicardial surface. Measurements were made during control conditions. Subjects - Thirty four anaesthetised mongrel dogs were studied. Measurements and main results - A total of 333 measurements of systolic excursion were made during control conditions at 1 to 3 crystal sites per dog. Two models were constructed; the model which assumed a quadratic relation between depth (d) and systolic excursion (EX) (EX = 0.498 + 0.176d + 0.006d2) fit the data better than did a model which assumed a linear relation (EX = −0.0716 + 0.254d). Conclusions - These data support the prediction from geometric models that systolic excursion increases in a non-linear fashion from subepicardium to subendocardium.
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