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Prolongation of repolarization in pre-clinical investigations and phase I/II clinical trials: what should be done?
Genetic aspects in acquired long QT syndrome — a piece in the puzzle
Mibefradil — a drug which may enhance the propensity for the development of abnormal QT prolongation
Influence of gender on drug-acquired long QT syndrome
Diversity of ion channel expression in health and disease
Native and cloned ion channels from human heart: laboratory models for evaluating the cardiac safety of new drugs
Drug-induced torsade de pointes: the perspectives of industry
The role of pharmacokinetics, drug interactions and pharmacogenetics in the acquired long QT syndrome
Heterogeneity of cellular repolarization in LQTS: the role of M cells
Preface
Spectrum of drugs prolonging QT interval and the incidence of torsades de pointes
Clinical aspects of ventricular arrhythmias associated with QT prolongation
Isolated tissue models and proarrhythmia
Focus on issues in measuring and interpreting changes in the QTc interval duration
Inhibition of repolarizing ionic currents by drugs
Drug-induced torsade de pointes: the perspectives of industry
Comparison of block among cloned cardiac potassium channels by non-antiarrhythmic drugs
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